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Journal: Current biology : CB

Article Title: Opposing Influence of Sensory and Motor Cortical Input on Striatal Circuitry and Choice Behavior

doi: 10.1016/j.cub.2019.03.028

Figure Lengend Snippet: KEY RESOURCES TABLE

Article Snippet: ​ REAGENT or RESOURCE SOURCE IDENTIFIER Bacterial and Virus Strains AAV1-CaMKII-hChR2(H134R)-eYFP.WPRE.hGH Addgene Addgene AAV1; 26969P pAAV-Ef1a-DIO eNpHR 3.0-EYFP Addgene Addgene AAV5; 26966-AAV5 Experimental Models: Organisms/Strains Mouse: B6.Cg-Tg(Drd1a-tdTomato)6Calak/J The Jackson Laboratory JAX: 016204 Mouse: B6.FVB(Cg)-Tg(DrD1cre)EY262Gsat/Mmucd Gensat Gsat: 030989-UCD Mouse: B6.FVB(Cg)-Tg(DrD2cre)ER44Gsat/Mmucd Gensat Gsat: 032108-UCD Mouse: B6.129P2-Pvalbtm1(cre)Arbr/J The Jackson Laboratory JAX: 008069 Mouse: Ai14 (cre-TdTomato) The Jackson Laboratory JAX: 007914 Mouse: Ai32 (cre-ChR2) The Jackson Laboratory JAX: 012569 Software and Algorithms MATLAB The Mathworks https://www.mathworks.com SAS SAS Institute https://www.sas.com/geohome.html Patchmaster HEKA https://www.heka.com LABVIEW National Instruments http://www.ni.com/en-us.html Data and Scripts Posted on Github https://github.com/margolislab/ctx-str Other Vibratome Leica VT1200S Cryostat ThermoFisher Scientific Shandon Cyrotome FSE Pipette Puller Sutter Instruments P-1000 Pipette Puller Sutter Instruments P-30 Vertical Puller Confocal Microscope Zeiss LSM800 AiryScan Amplifier HEKA EPC10 Fixed Upright Microscope Olympus BX51WI Open in a separate window KEY RESOURCES TABLE S1 provides stronger input to striatal PV neurons than spiny projection neurons M1 provides equal input to striatal PV neurons and spiny projections neurons S1- and M1-corticostriatal inputs exert opposing influence on choice behavior Manipulation of striatal PV neurons bidirectionally influences choice behavior

Techniques: Software, Transferring, Microscopy